American Orient Express Trains Takes 2 or 3 Routes from Amtrak - Trains Magazine

Interesting idea, but the American Orient Express is very expensive to ride on: Liability, Operation over host railroads, Crew costs, Equipment maintenence, etc., are among the reasons. Currently to book a tour (at least a year in advance) is going to run in the thousand dollar digit.

The Amtrak Empire Builder, Crescent, and Silver Service trains and especially the Auto Train are among the long distance trains that do well ridership wise.